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Author Title Reference Year View Applications
Jordan, G et al : Platform switching from ELISA to Gyrolab™: a novel generic reagent omits the need to change critical reagents Bioanalysis 2016 Apr;8(8):807-14 2016 Read Pharmacokinetics
Wang, J et al : Antibody–drug conjugate bioanalysis using LB-LC–MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding Bioanalysis 2016 Jul;8(13):1383-401 2016 Read Antibody-Drug Conjugates
Quaranta, A et al N-Glycan profile analysis of transferrin using a microfluidic compact disc and MALDI-MS Analytical and Bioanalytical Chemistry (2016) 408:4765–4776 2016 Read Other
Collet-Brose, J et al Evaluation of Multiple Immunoassay Technology Platforms to Select the Anti-Drug Antibody Assay Exhibiting the Most Appropriate Drug and Target Tolerance Journal of Immunology Research 2016 Read Immunogenicity
Avery, LB et al Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies mAbs 2016 May 27:1-15. [Epub ahead of print] 2016 Read Pharmacokinetics
Almquist, J et al Unraveling the pharmacokinetic interaction of ticagrelor and MEDI2452 (Ticagrelor antidote) by mathematical modeling CPT Pharmacometrics Systems Pharmacology 2016 Jun;5(6):313-23 2016 Read Other,Pharmacokinetics
Myler, H et al Validation of an integrated series of ligand-binding assays for the quantitative determination of antibody–drug conjugates in biological matrices Bioanalysis (2016) 8(6), 519–531 2016 Read Antibody-Drug Conjugates
Partridge, M A et al Emerging Technologies and Generic Assays for the Detection of Anti-Drug Antibodies Journal of Immunology Research 2016 Read Immunogennicity
Weirong, W et al Deciphering the In Vivo Performance of a Monoclonal Antibody to Neutralize Its Soluble Target at the Site of Action in a Mouse Collagen-Induced Arthritis Model Pharmaceutical Research, 2016, 1-10 2016 Read Pharmacokinetics
Myzithras M Development of an ultra-sensitive Simoa assay to enable GDF11 detection: a comparison across bioanalytical platforms Bioanalysis (2016) 8(6), 511–518 2016 Read Biomarker Monitoring
Lanshoeft, C et al Quantitative analysis of hIgG1 in monkey serum by LC–MS/MS using mass spectrometric immunoassay Bioanalysis 2016 May;8(10):1035-49 2016 Read Pharmacokinetics
Hammond, M. M1041 - Development of an Immunogenicity Assay Format for Use in Preclinical Monkey Studies Using the Gyrolab Platform 2015 AAPS NBC 2015 PDF of abstract Immunogenicity
Liu, PM et al Comparative immunogenicity assessment: a critical consideration for biosimilar development Bioanalysis (2015) 7(3) 2015 Read Immunogenicity
Hartmann, S et al Developability of Biotherapeutics books.google.com 2015 Other
Burns, EC et al 16th Annual Land O’Lakes Bioanalytical Conference - Conference Report Bioanalysis Vol. 7, No. 21, Pages 2731-2734 2015 Read Other
Keil, G High-throughput screening and automation approaches for the development of recombinant therapeutic proteins Pharm. Bioprocess. (2015) 3(5), 371–380 2015 Read Other
Cris Macaraeg et al Serum sample stability in ligand-binding assays: challenges in assessments of long-term, bench-top and multiple freeze–thaw Bioanalysis (2015) 7(11), 1361–1370 2015 Read Pharmacokinetics
Wiberg, A et al Characterization of Human Organ Donors Testing Positive for Type 1 Diabetes-Associated Autoantibodies Clinical Experimental Immunology 2015 Dec;182(3):278-88 2015 Read Biomarker Monitoring
Welsh, J P et al Domain antibody downstream process optimization: High-throughput strategy and analytical methods Engineering in Life Sciences, DOI: 10.1002/elsc.201400255 2015 Read Impurity Testing
Caron, A et al Miniaturized Blood Sampling Techniques to Benefit Reduction in Mice and Refinement in Nonhuman Primates: Applications to Bioanalysis in Toxicity Studies with Antibody–Drug Conjugates Journal of the American Association for Laboratory Animal Science, Vol 54, No 2 March 2015 Pages 145-152 2015 Read Pharmacokinetics
Saad, OM et al Bioanalytical approaches for characterizing catabolism of antibody–drug conjugates Bioanalysis (2015) 7(13) 2015 Read Pharmacokinetics,Antibody-Drug Conjugates
Kang, Y et al Development of an acidic/neutral antibody flow-through polishing step using salt-tolerant anion exchange chromatography Pharm. Bioprocess. (2015) 3(8), 477–487 2015 Read Impurity Testing
Cai, H et al Automation of ELISAs & evaluation of emerging technologies for high-throughput quantitation of protein impurities Pharm. Bioprocess. (2015) 3(7), 427–441 2015 Read Impurity Testing
Vettermann, C et al Indirect assessment of neutralizing anti-drug antibodies utilizing pharmacokinetic assay data Journal of Immunological Methods S0022-1759(15)30076-4 2015 Read Pharmacokinetics
Lu, X. et al Development of an Immunoassay with Gyrolab Workstation for the Quantification of sAXL in Mouse and Human Plasma 2015 AAPS NBC 2015 PDF of abstract Biomarker Monitoring
Hsieh, S. et al M1053 - Immunogenicity Assay Development on the Gyrolab Platform: Increasing Sensitivity and Drug Tolerance 2015 AAPS NBC 2015 PDF of abstract Immunogenicity
Tibbitts, J et al Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development mAbs 2015 Read Antibody-Drug Conjugates
Ehlinger, C. et al M1040 - Generic Drug Tolerant Immunogenicity Assay to Detect Rat Antibodies against Human Antibody Drugs Using the Gyrolab xP Workstation 2015 AAPS NBC 2015 PDF of abstract Immunogenicity
Elango, C. et al M1024 - Development of an Immunogenicity Assay Using Gyrolab Platform for a Therapeutic Monoclonal Antibody (Mab) 2015 AAPS NBC 2015 PDF of abstract Immunogenicity
Ramsubramaniam, N Rapid Process Development Enabled by Automated, Single Use High Throughput Technologies 2015 Annual Meeting of the Society for Industrial Microbiology & Biotechnology, Session 22: Fermentation/Cell Culture: Biologics: Delivering Innovation to Industry and Patients Alike 2015 Read Impurity Testing,Product Quantification
Davidsson, P et al. Studies of Nontarget‐Mediated Distribution of Human Full‐Length IgG1 Antibody and Its FAb Fragment in Cardiovascular and Metabolic‐Related Tissues Journal of Pharmaceutical Sciences, Vol. 104, Volume 104, Issue 5, pages 1825-1831, May 2015 2015 Read Pharmacokinetics
Ryan, P C et al Nonclinical safety of mavrilimumab, an anti-GMCSF receptor alpha monoclonal antibody, in cynomolgus monkeys: Relevance for
human safety
Toxicology and Applied Pharmacology 279 (2014) 230–239 2015 Read Other
Tang, D et al The 3rd China Bioanalysis Forum annual meeting Bioanalysis (Epub ahead of print) 2015 Read Other
Kumar, S et al Antibody–drug conjugates nonclinical support: from early to late nonclinical bioanalysis using ligand-binding assays Bioanalysis (2015) 7(13), 1605–1617 2015 Read Antibody-Drug Conjugates
Howard, D et al Delivering rhFGF-18 via a bilayer collagen membrane to enhance microfracture treatment of chondral defects in a large animal model Journal of Orthopaedic Research, Accepted 7 February 2015 2015 Read Biomarker Monitoring
Wadhwa, M et al Immunogenicity assessment of biotherapeutic products: An overview of assays and their utility Biologicals (2015) 1-9 2015 PDF Immunogenicity
Qui, ZJ et al Strategies to compare clinical antitherapeutic antibody data when changing assay platforms: a case study Bioanalysis (2015) 7(14) , 1775–1783 2015 Read Immunogenicity
Shang, J et al Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic Beta-Cells Molecular Endocrinology, doi: 10.1210/me.2014-1335 2015 Read Biomarker Monitoring
Hartmann, S et al 7 Best Practices in Assessment of Developability of Biopharmaceutical Candidates Developability of Biotherapeutics: Computational 2015 Learn more
Burns, D et al Improving Efficiency and Data Reproducibility through the Use of Fully Integrated Automation in Bioanalysis of Biotherapeutics AAPS 2014 Poster Other
Joyce, AP, et al One Mouse, One Pharmacokinetic Profile: Quantitative Whole Blood Serial Sampling for Biotherapeutics Pharm Res. 2014 Jan 24 2014 PMID Pharmacokinetics
Fraser, S, et al Active glucagon-like peptide 1 quantitation in human plasma: A comparison of multiple ligand binding assay platforms Journal of Immunological Methods, April 8 2014 Read Other
Faleri, A, et al Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties. Journal of Immunological Methods, April 8 2014 PMID Other,Vaccines
Collet, J et al

Evaluating Multiple Technology Platforms to Meet Challenges of Developing a Ligand Binding Assay to Support Clinical Trials Conducted in Adult or Pediatric Populations AAPS 2014 Poster Pharmacokinetics
Nazneen, B Binding of Autoantibodies Varies Widely between β1-Adrenergic Receptor (β1-AR) Constructs AAPS 2014 Poster Immunogenicity
Zoghbi, J A breakthrough novel method to resolve the drug and target interference problem
in immunogenicity assays
J Immunol Methods. 2015 Nov;426:62-9. 2014 Read Pharmacokinetics
Verch, T Application of quality by design and statistical quality control concepts in immunoassays Bioanalysis (2014) 6(23), 3251–3260 2014 Read Other
Salimi-Moosavi, H et al A Multifactorial Screening Strategy to Identify Anti-Idiotypic Reagents for Bioanalytical Support of Antibody Therapeutics Analytical Biochemistry S0003-2697(14)00452-7 2014 Read Pharmacokinetics
Heo, JH et al. A microfluidic approach to high throughput quantification of host cell protein impurities for bioprocess development Pharmaceutical Bioprocessing Vol. 2, No. 2, Pages 129-139. 2014 Read Impurity testing
Faleri, A et al Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties The FASEB Journal Vol. 28 April 2014 1644-1653 2014 Read Other
Liu, XF et al. Assessing Effects of Freeze-Thaw on Biotinylated Macromolecules Using Gyrolab™ J Bioanal Biomed 6: 049-051 2014 PDF Other
Kozhich, A et al Multiparameter Comparison of PK Immunoassay for a Therapeutic Monoclonal Antibody Implemented on Four Different Platforms AAPS 2014 Poster Pharmacokinetics
Chakravarthy, K et al Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis BMC Musculoskeletal Disorders 2014, 15:409 2014 Read Pharmacokinetics
Magana, I et al Validation of a microfluidic platform to measure total therapeutic antibodies and incurred sample reanalysis performance Bioanalysis (2014) 6(19), 2623–2633 2014 Read Pharmacokinetics
Dysinger, M et al Biomarker Quantitation on GyroLab Platform: A Case for a Two Step Assay AAPS 2014 Poster Biomarker Monitoring
Cameron, M. J. et al A Gyros Platform Advanced Immunoassay Validation of E-Selectin as a Safety Biomarker for Vascular Injury in Rat AAPS 2014 Poster Biomarker Monitoring
Shen,C et al Urine Urea Impacts the Accuracy of Soluble Vascular Cell Adhesion Molecule 1 (sVCAM-1) Urinary Immunoassay AAPS 2014 Poster Biomarker Monitoring
Giddabasappa, A et al Abstract 4293: Whole-body bio-distribution of anti-5T4-mcMMAF (anti-5T4-ADC) using fluorescence molecular tomography (FMT) imaging in a non-small cell lung cancer mice model. Cancer Res October 1, 74; 4293 2014 Read Pharmacokinetics
Salimi-Moosavi, H et al. A Multifactorial Screening Strategy to Identify Anti-Idiotypic Reagents for Bioanalytical Support of
Antibody Therapeutics.
Anal Biochem 2015, Feb 1; 470:52-60. Epub 2014 Oct 27. 2014 Read Other
Chakravarthy, K et al. Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis BMC Musculoskeletal Disorders 2014, 15:409 2014 Read Pharmacokinetics
Patel, V et al Automating bioanalytical sample analysis through enhanced system integration Bioanalysis 2013 Jul;5(13):1649-59 2013 PMID Other,Pharmacokinetics
Park, W et al A randomised, double-blind, multicentre, parallel-group, prospective study comparing the pharmacokinetics, safety, and efficacy of CT-P13 and innovator infliximab in patients with ankylosing spondylitis: the PLANETAS study Ann Rheum Dis 2013;0:1–8. 2013 Read Pharmacokinetics
Fraley, KJ et al The Gyrolab™ immunoassay system: a platform for automated bioanalysis and rapid sample turnaround Bioanalysis 2013 Jul;5(14):1765-74 2013 Read Other
Piper, E et al A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma Eur Respir J. 2013 February; 41(2): 330–338 2013 Read Pharmacokinetics,Immunogenicity
Liu, R et al Rapid development of multiple 'fit-for-purpose' assays on an automatic microfluidic system using a streamlined process in support of early biotherapeutics discovery programs Bioanalysis 2013 Jul;5(14):1751-63 2013 Read Pharmacokinetics
Ishino, T et al Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics J. Biol. Chem., Jun 2013; 288: 16529 - 16537 2013 PMID Other
Hall, CM et al An extended range generic immunoassay for total human therapeutic antibodies in preclinical pharmacokinetic studies J Immunol Methods. 2013 Jul 31;393(1-2):70-3 2013 PMID Pharmacokinetics
Thuy, TT et al Glycosylation Profiling of Therapeutic Antibodies in Serum Samples Using a Microfluidic CD Platform and MALDI-MS J. Am. Soc. Mass Spectrom (2013) 2013 PMID Other
Spensieri, F et al Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses PNAS, Aug 2013; 110: 14330 - 14335. 2013 PMID Vaccines
Leary, BA et al Bioanalytical platform comparison using a generic human IgG PK assay format J Immunol Methods. 2013 Aug 29. pii: S0022-1759(13)00234-2. 2013 Read Other
Sampei, Z et al Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity PLoS ONE 8(2): e57479 2013 Read Pharmacokinetics
Goodman, J et al Analytical assay platforms for soluble target engagement biomarkers: old favorites and emerging technologies Bioanalysis (2013) 5(23), 2919–2931 2013 Read Pharmacokinetics
Georgievska, B et al AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans. J Neurochem. 2013 May;125(3):446-56. 2013 PMID Biomarker Monitoring
Henderson, SJ et al Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β Brain (2013) doi: 10.1093/brain/awt308 2013 Read Pharmacokinetics
Jonsson, O et al Capillary microsampling and analysis of 4-μl blood, plasma and serum samples to determine human a-synuclein elimination rate in mice Bioanalysis 2013, 5(5) 449-462 2013 Read Pharmacokinetics
Gonzales, AJ et al Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis Vet Dermatol 2013, 24: 48-e12 2013 PDF Biomarker Monitoring
Salimi-Moosavi, H et al Rapid affinity measurement of protein-protein interactions in a microfluidic platform. Anal Biochem. 2012 Jul 15;426(2):134-41. 2012 PMID Other
Liu, XF et al Validation of a gyrolab™ assay for quantification of rituximab in human serum Journal of Pharmacological and Toxicological Methods 2012 Read Pharmacokinetics
Given, AM et al Development and validation of an alpha fetoprotein immunoassay using Gyros technology. J Pharm Biomed Anal. 2012 May;64-65:8-15. 2012 PMID Biomarker Monitoring
Shih, J et al Implementation of a universal analytical method in early-stage development of human antibody therapeutics: application to pharmacokinetic assessment for candidate selection Bioanalysis 2012, 4(19) 2357-2365 2012 Read Pharmacokinetics
Thuy, TT et al Discrimination between glycosylation patterns of therapeutic antibodies using a microfluidic platform, MALDI-MS and multivariate statistics J Pharm Biomed Anal. 2012 Nov;70:47-52 2012 PMID Other
Liu, XF et al Validation of a Gyrolab™ assay for quantification of rituximab in human serum J Pharmacol Toxicol Methods, 2012, 65 (3) 107-114 2012

PMID Pharmacokinetics
Eckersten, A et al Development of an automated ADA immunoassay with integrated acid dissociation and neutralization 2011 PDF Immunogenicity
Wang, W et al Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies Mol Immunol 2011, 48 860-866, doi:10.1016/j.molimm.2010.12.009 2011 PMID Pharmacokinetics
Gustafsson, K et al Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells BMC Immunol. 2011 12:3. doi: 10.1186/1471-2172-12-3. 2011 PMID Biomarker Monitoring
Peiris, KJ et al Development of residual host cell protein assays for recombinant microbial biopharmaceuticals 5th Annual European Gyrolab Seminar, Siena, Italy 2011 PDF Impurity Testing
Thuy, TT et al High-throughput profiling of N-linked oligosaccharides in therapeutic antibodies using a microfluidic CD platform and MALDI-MS Anal Bioanal Chem (2011) 399:1601–1611 2011 PMID Other
Allinson, J L Automated immunoassay equipment platforms for analytical support of pharmaceutical and biopharmaceutical development Bioanalysis (2011) 3(24), 2803–2816 2011 Read Other
Eibl, R et al The Manufacture of mAbs - A Comparison of Performance and Process Time between Traditional and Ready-to-Use Disposable Systems Single-Use Technology in Biopharmaceutical Manufacture, Published Online: 19 Jan 2011 DOI: 10.1002/9780470909997.ch28 2011 Impurity Testing
Ni, YG et al A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo J Lipid Res 2011, 52(1) 78-86. 2011 PMID Other,Pharmacokinetics
Brady, K Addressing Ligand Binding Assay Deficiencies Genetic Engineering & biotechnology News 2009, 29 (14) 33 2010 Other
Boyer, S et al Evaluation of Tau Phosphorylation using a Non-Traditional Immunoassay Platform 4th Annual European Gyrolab Seminar 2010 PDF Biomarker Monitoring
Somerfield, J et al A novel strategy to reduce the immunogenicity of biological therapies J Immunology 2010, 185 (1) 763-768 2010 PMID Immunogenicity,Product Quantification
Colombo, L et al New analytical technologies: Pharmaceutical applications to proteins and antibodies. An industry perspective National meeting on medicinal chemistry (NMMC), Abano Terme, Italy, Book of abstracts, p39-40, October 2010 2010 Biomarker Monitoring,Immunogenicity,Impurity Testing,Pharmacokinetics
Mallozzi, C & Kavosi, M Gyrolab Demonstrated Shorter Assay Time and Broader Dynamic Range Compared to a Plate Based ELISA with a Generic Human IgG Assay in Rat Serum Inaugural North American Gyrolab Seminar 2010 PDF Pharmacokinetics
Eckersten, A et al Validation of a ligand binding assay 4th Annual European Gyrolab Seminar 2010 Validation
Salimi-Moosavi, H High Throughput Ligand Binding Assay for Therapeutic Antibodies and Biomarkers Using Gyros Microfluidic Instrument NBC Symposium: Advantages of Non-Traditional Technologies for Ligand Binding Assay Development, 2010 2010 PDF Pharmacokinetics
Poelmans, S et al Immunogenicity monitoring during preclinical development of Nanobodies¨: comparing assay formats and species matrices AAPS 2010 PDF Immunogenicity
Thomas, AK et al Evaluation of in vitro and in vivo tau phosphorylation using the Gyros immunoassay platform Society for neurosciences meeting November 2010 2010 PDF Biomarker Monitoring
Shen, H-W & Yu, A-M New analytical technologies for biological discovery Bioanalysis 2010, 2(2), 181-184 2010 Read Pharmacokinetics
Brady, K Utility of the Gyros Gyrolab in Research and DMPK - an automated ligand binding assay platform 2010 PDF Immunogenicity,Product Quantification
von Horsten, H Production of Non-fucosylated Antibodies by Co-Expression of Heterologous GDP-6-deoxy-D-lyxo-4-hexulose reductase Glycobiology. 2010, 20 (12) 1607-18. 2010 PDF Product Quantification
Roman, J et al Application of miniaturized immunoassays to discovery pharmacokinetic bioanalysis J Pharmacological Toxicological Methods, online December 2010 2010 PDF Pharmacokinetics
Sadeghi, B et al Expansion and Activation Kinetics of Immune Cells during Early Phase of GVHD in Mouse Model Based on Chemotherapy Conditioning Clin Dev Immunol. 2010, 142943. doi: 10.1155/2010/142943. Epub 2010 Dec 21. 2010 PMID Biomarker Monitoring
van der Woude, C et al Phase I, Double-blind, Randomized, Placebo-controlled, Dose-escalation Study of NI-0401 (a Fully Human Anti-CD3 Monoclonal Antibody) in Patients with Moderate to Severe Active Crohn̥s Disease Inflamm Bowel Dis. 2010, 16(10) 1708-16 2010 PMID Pharmacokinetics
Mora, J et al Application of the Gyrolab platform to ligand-binding assays: a user's perspective Bioanalysis 2010, 2 (10) 1711-1715 2010 PMID Impurity Testing,Immunogenicity,Pharmacokinetics
Thuy, TT et al Parallel sample preparation of proteins, from crude samples to crystals ready for MALDI-MS, in an integrated microfluidic system J Chromatogr B Analyt Technol Biomed Life Sci, 2010 Oct 15;878(28):2803-10 2010 PMID Other
Lund, T et al Resolvin E1 reduces proinflammatory markers in human pancreatic islets in vitro Exp Clin Endocrinol Diabetes. 2010, 118(4) 237-44 2010 PMID Biomarker Monitoring
Hannam, S et al Minimising Volume, Maximising Returns European Pharmaceutical Review, Discovery Technology, Spring 2010 2010 Read Biomarker Monitoring,Pharmacokinetics,Free PD Marker
Singh, D et al A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma BMC Pulm Med. 2010, 8 10:3. 2010 PMID Pharmacokinetics
Oh, C K et al An open-label, single-dose bioavailability study of the pharmacokinetics of CAT-354 after subcutaneous and intravenous administration in healthy males Brit J Pharmacol 2010, 69 (6) 645-655 2010 PMID Pharmacokinetics
Cameau, E et al Evaluation of a Single-Use Bioreactor for the Fed-Batch Production of a Monoclonal Antibody BioPharm International Supplements, Nov. 2010 2010 Product Quantification
Wallby, E et al Gyrolab applications in industrial monoclonal antibody development 2009 PDF Impurity Testing
He, H et al Design and testing of a microfluidic biochip for cytokine enzyme-linked immunosorbent assay Biomicrofluidics. 2009, 3 (2) 22401 2009 PMID Biomarker Monitoring
Clizbe, D et al Increased sample volume improves ability to quantify cytokines in Gyrolab Bioaffy 1000 2009 PDF Biomarker Monitoring
Paulsen, J Analyses of AKT and PDGF receptor expression and activation in human tumors PhD thesis ISBN: 978-91-7409-504-3 2009 Biomarker Monitoring,Other
Lehtonen, P & Inganas, M Quantification of MabSelect SuRe ligand in presence of excess amounts of IgG on Gyrolab 2009 PDF Impurity Testing
Kelley, M Gyrolab in a validated environment Gyrolab Seminar, 2009 2009 PDF Validation
Johansson, U et al Formation of Composite Endothelial Cell-Mesenchymal Stem Cell Islets A Novel Approach to Promote Islet Revascularization Diabetes 2008, 57 (9) 2393-2401 2008 PMID Biomarker Monitoring
Jonson, C-O Regulatory T cell-associated activity in photopheresis-induced immune tolerance in recent onset type 1 diabetes children Clin Exp Immunol. 2008, 153 (2) 174-181 2008 PMID Biomarker Monitoring
Bishop, E Use of Gyrolab in Biotechnology Process Development Gyrolab Seminar 2008 PDF Impurity Testing
Linneberg, A et al Effects of Alcohol Consumption on the Allergen-Specific Immune Response in Mice Alcoholism: Clin and Expl Res. 2008, 32 (3) 553-557 2008 PMID Biomarker Monitoring
Osterlund, K et al Automated protein quantification in bioprocess development and pharmacokinetic studies: Improving assay performance Merck Technology Symposium 2007 PDF Impurity Testing
Andersson, P et al Parallel nanoliter microfluidic analysis system Anal Chem. 2007, 79 (11) 4022-4030 2007 PMID Other
Lehtonen, P et al Improved analytical tools for quantification of monoclonal IgG and host cell proteins during biopharmaceutical process development WCBP 2007 Impurity Testing,Product Quantification
Mayans, S et al CT60 genotype does not affect CTLA-4 isoform expression despite association to T1D and AITD in northern Sweden BMC Medical Genetics 2007, 8:3 2007 PMID Biomarker Monitoring
Honda, N et al Simultaneous Multiple Immunoassays in a Compact Disc-Shaped Microfluidic Device Based on Centrifugal Force Clin Chem 2005, 51 (10) 1955-1961 2005 PMID Biomarker Monitoring
Rivera, E et al The Rb1 fraction of ginseng elicits a balanced Th1 and Th2 immune reponse Vaccine 2005, 23 (46-47) 5411-5419 2005 PMID Biomarker Monitoring, Vaccines
Inganas, M et al Determining cytokine levels from small sample volumes in vaccine studies using Gyrolab Bioaffy 12th International Congress of Immunology and 4th Annual Conference of FOCIS Montreal, Canada, July 18-23, 2004 2004 Biomarker Monitoring,Vaccines
Inganäs, M Application Report 205: Quantification of antigen-specific antibodiesin serum Gyros Application Report Product Information Vaccines
Crosasso, C et al Gyrolab in a GxP environment: the Merck Serono experience PDF Pharmacokinetics
Inganäs, M Application Report 204: Insulin quantification:save sample and increase efficiency Gyros Application Report Product Information Biomarker Monitoring
Inganäs, M Application Report 207: Miniaturizing immunoassays for improved performance Gyros Application Report Product Information Biomarker monitoring,Pharmacokinetics,Product Quantification
Inganäs, M Application Report 206: Single-system solution for quantification of monoclonal IgG and host cell proteins (HCP) Gyros Application Report Product Information Impurity Testing



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