RecipharmCobra Biologics
Biopharmaceutical development at RecipharmCobra Biologics
An example of how Gyrolab can be implemented as the immunoassay platform from start to finish is presented by Dr Anders Hagman. A variety of applications from cell line development, via cell culture development and purification process development and through to QC Release testing and their respective advantages on Gyrolab is discussed.
Probiogen
High Accuracy Quantification of Therapeutic Proteins in Pharmaceutical Cell Line Development
Dr Horsten decribes his work using Gyrolab for quantification of therapeutic proteins and compares data generated on Gyrolab with corresponding data generated with ELISA, HPLC and MSD. Orthogonality between the methods is investigated and discussed.
Product quantification in pharmaceutical cell line development
Dr Von Horsten outlines the changing requirements for quantification assays including case studies showing quantification results for several different therapeutic proteins using the Gyrolab SIA Application assay format. Comparisons are made with classical ELISA and HPLC methods.
Lonza
Biopharmaceutical manufacturing in microbial systems - Gyrolab as an analytical platform supporting process development
Biopharmaceutical manufacturing in microbial systems – evaluation of Gyrolab as an alternative tool to support process development and subsequent production.
Dr Wegmann summarizes his experience of using the Gyros immunoassay platform as an alternative method to support process development activities and subsequent production of API’s, with particular regard to method performance and development time