Ablynx
Development and validation of a biomarker assay to measure free antigen levels in cynomolgus monkey plasma
When traditional assay formats failed, a robust and sensitive biomarker assay to measure free antigen levels was developed. Dr DeNeve presents development, validation and results and describes the rationale for choosing the Gyros platform for this application.
Pfizer
Gyrolab at Pfizer UK
Dr Brady discusses current biologics and biomarker assay development and the impact that the Gyros platform has had. A comparison is made with existing assay formats. Advantages of outsourcing the assay format are explained and the vast improvement in data is demonstrated
GlaxoSmithKline
Development of a Preclinical PD Assay: solving needle carryover
Development and validation of a biomarker assay to quantify levels of free analyte in human synovial fluid
Dr Goodman describes the development and validation of a free analyte assay using ICH guidelines and the potential for reduced drug interference in the total analyte assay when compared to a previously validated assay.
Quotient Bioresearch
Application of the Gyrolab in PK, Immunogenicity & PD analysis
Dr. Gaskell details how the flexibility of the Gyrolab platform allows for pharmacokinetic, immunogenicity and pharmacodynamic studies in different matrices