
	Protein Quantification

	Overview

	Protein quantification at nanoliter scale

	Single system solution for quantification of monoclonal IgG and host cell proteins

	Increasing efficiency in biopharmaceutical process development

	Pharmacokinetics of therapeutic antibodies

	Quantification of antigen-specific antibodies in serum

	Insulin quantification: save sample and increase efficiency

	Cytokine quantification in small animal models




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Applications Overview

Gyros technology is founded on an open flexible platform. It provides significant benefits across a broad range of protein applications within drug discovery and development, as well as good potential for future development in diagnostic applications.

Currently, Gyros applications are focused on protein quantification.

Protein Quantification
Based on the well-established sandwich immunoassay format, Gyrolab Bioaffy is well suited to a wide range of protein quantification applications. Any protein can be assayed as long as a suitable binding pair (capture and detection reagents) is available.

Protein quantification at nanoliter scale
Miniaturization and integration of sandwich immunoassays into a CD microlaboratory. Automated, parallel processing delivers fast, reliable results and generates more information from less sample.

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Single system solution for quantification of monoclonal IgG and host cell proteins
Gyrolab Bioaffy® offers a unique solution for protein quantification in biopharmaceutical process development:

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Increasing efficiency in biopharmaceutical
process development
Significantly increased throughput and reduction of operator 'hands-on' time, whilst still delivering high quality results.

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Quantification of antigen-specific antibodies in serum
Together with the National Veterinary Institute (SVA), Sweden, a bridging assay has been developed to monitor the progress of antibody responses in mice immunized with porcine parvovirus (PPV) vaccine preparations using Gyrolab Bioaffy^®.

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Insulin quantification: save sample and increase efficiency
An efficient tool for high throughput insulin quantification, matching current technologies in terms of assay performance, whilst reducing sample and reagent consumption.

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Cytokine quantification in small animal models
Nanoliter sample volumes and the ability to measure cytokines directly in mouse serum allow detection of biological response at an earlier stage, shortening overall vaccine development times.

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